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Significance of the p38MAPK-CRP2 axis in myofibroblastic phenotypic transition

We have recently demonstrated that a LIM domain protein, cysteine and glycine-rich protein 2 (CSRP2 [CRP2]), plays a vital role in the functional expression of myofibroblasts and cancer-associated fibroblasts. CRP2 binds directly to myocardin-related transcription factors (MRTF [MRTF-A or MRTF-B]) a...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Ken’ichiro Hayashi, Reuben Jacob Labios, Tsuyoshi Morita, Atsushige Ashimori, Ren Aoki, Masanori Mikuni, Kazuhiro Kimura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japan Society for Cell Biology 2023-10-01
Schriftenreihe:Cell Structure and Function
Schlagworte:
Online-Zugang:https://www.jstage.jst.go.jp/article/csf/48/2/48_23060/_html/-char/en
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