Reduced Levels of miR-145-3p Drive Cell Cycle Progression in Advanced High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most lethal form of gynecologic cancer, with limited treatment options and a poor prognosis. Epigenetic factors, such as microRNAs (miRNAs) and DNA methylation, play pivotal roles in cancer progression, yet their specific contributions to HGSOC remain...

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Hlavní autoři:	Eva González-Cantó, Mariana Monteiro, Cristina Aghababyan, Ana Ferrero-Micó, Sergio Navarro-Serna, Maravillas Mellado-López, Sarai Tomás-Pérez, Juan Sandoval, Antoni Llueca, Alejandro Herreros-Pomares, Juan Gilabert-Estellés, Vicente Pérez-García, Josep Marí-Alexandre
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-11-01
Edice:	Cells
Témata:	high-grade serous ovarian cancer miRNAs DNA methylation miR-145-3p cell cycle proliferation cyclin D1-CDK4/6 pathway
On-line přístup:	https://www.mdpi.com/2073-4409/13/22/1904
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