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Demyelination Lesions Do Not Correlate with Clinical Manifestations by Bordetella pertussis Toxin Concentrations

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, characterized as an inflammatory demyelinating disease. Given the need for improvements in MS treatment, many studies are mainly conducted through preclinical models such as experimental allergic encephalomyelitis (EAE)....

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Principais autores: Maiara Carolina Perussolo, Bassam Felipe Mogharbel, Claudia Sayuri Saçaki, Dilcele Silva Moreira Dziedzic, Seigo Nagashima, Leanderson Franco de Meira, Luiz Cesar Guarita-Souza, Lúcia de Noronha, Katherine Athayde Teixeira de Carvalho
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Life
Fag:
experimental allergic encephalomyelitis
multiple sclerosis
histopathological
<i>Bordetella pertussis</i> toxin
clinical scores
animal model
Online adgang:https://www.mdpi.com/2075-1729/12/7/962
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