Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

IntroductionCerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common genetic small vessel disease caused by variants in the NOTCH3 gene. Patients with CADASIL experience recurrent strokes, developing into cognitive defect and vascular de...

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Κύριοι συγγραφείς:	Wenjun Zhang, Xiangjun Zhao, Xuewei Qi, Susan J. Kimber, Nigel M. Hooper, Tao Wang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2023-06-01
Σειρά:	Frontiers in Cellular Neuroscience
Θέματα:	CADASIL genetic small vessel disease neurovascular interaction blood-brain barrier neurovascular unit
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1195470/full
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