Astragalin Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis and in Human Fibroblast-Like Synoviocytes

Astragalin, as a bioactive flavonoid with anti-inflammatory, antioxidant, and protective properties, provides a potential agent for rheumatoid arthritis (RA). In this study, its therapeutic efficacy and the underlying mechanisms were explored using DBA/1J mice with collagen-induced arthritis (CIA)....

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Bibliografische Detailangaben

Hauptverfasser:	Qingyun Jia, Tengteng Wang, Xiaoyun Wang, Hao Xu, Yang Liu, Yongjun Wang, Qi Shi, Qianqian Liang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2019-02-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	astragalin rheumatoid arthritis matrix metalloproteinase CIA fibroblast-like synoviocytes
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fphar.2019.00094/full
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