Bridging prion biology and Alzheimer’s disease: from pathogenic seeds to precision therapeutics

Alzheimer’s disease (AD) is characterized by the pathological aggregation of amyloid-beta (Aβ) and tau proteins, which display self-templating propagation reminiscent of the prion protein (PrPSc). Despite these similarities, distinct structural heterogeneities and host interaction mechanisms offer u...

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Bibliografske podrobnosti

Principais autores:	Wenjin Wang, Zhanhui Feng, Lingfeng Shu, Yongmei Hu, Yuting Chen, Baihui Zhang, Hua Huang
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-10-01
Serija:	Frontiers in Molecular Neuroscience
Teme:	Alzheimer’s disease amyloid-beta tau protein prion conformational propagation precision intervention
Online dostop:	https://www.frontiersin.org/articles/10.3389/fnmol.2025.1660151/full
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