Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

Flaviviruses replicate in membrane factories associated with the endoplasmic reticulum (ER). Significant levels of flavivirus viral protein accumulation contribute to ER stress. As a consequence, the host cell exhibits an Unfolded Protein Response (UPR), subsequently stimulating appropriate cellular...

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Hlavní autoři:	Grégorie Lebeau, Jonathan Turpin, Etienne Frumence, Daed El Safadi, Wissal Harrabi, Philippe Desprès, Pascale Krejbich-Trotot, Wildriss Viranaïcken
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-05-01
Edice:	Viruses
Témata:	Zika virus unfolded protein response ER stress oligomer disulfide bond amyloid aggregates
On-line přístup:	https://www.mdpi.com/1999-4915/14/6/1131
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