QR Code

GNNGL-PPI: multi-category prediction of protein-protein interactions using graph neural networks based on global graphs and local subgraphs

Abstract Most proteins exert their functions by interacting with other proteins, making the identification of protein-protein interactions (PPI) crucial for understanding biological activities, pathological mechanisms, and clinical therapies. Developing effective and reliable computational methods f...

Full description

Saved in:
Main Authors: Xin Zeng, Fan-Fang Meng, Meng-Liang Wen, Shu-Juan Li, Yi Li
Format: Artigo
Language:Inglês
Published: BMC 2024-05-01
Series:BMC Genomics
Subjects:
Multi-category prediction of protein-protein interactions
Graph neural network
Global graphs
Local subgraphs
Asymmetric loss function
Online Access:https://doi.org/10.1186/s12864-024-10299-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items