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The H2S Donor Sodium Thiosulfate (Na2S2O3) Does Not Improve Inflammation and Organ Damage After Hemorrhagic Shock in Cardiovascular Healthy Swine

We previously demonstrated marked lung-protective properties of the H2S donor sodium thiosulfate (Na2S2O3, STS) in a blinded, randomized, controlled, long-term, resuscitated porcine model of swine with coronary artery disease, i.e., with decreased expression of the H2S-producing enzyme cystathionine...

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Uloženo v:
Hlavní autoři: David Alexander Christian Messerer, Holger Gaessler, Andrea Hoffmann, Michael Gröger, Kathrin Benz, Aileen Huhn, Felix Hezel, Enrico Calzia, Peter Radermacher, Thomas Datzmann
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-06-01
Edice:Frontiers in Immunology
Témata:
physical injuries
hemorrhage
systemic inflammation
hydrogen sulfide
animal model
gaseous mediator
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.901005/full
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