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Trans-eQTLs Can Be Used to Identify Tissue-Specific Gene Regulatory Networks

Previous high-throughput screening studies have indicated that trans-eQTLs tend to be tissue-specific. This study investigates whether this feature can be used to identify tissue-specific gene regulatory networks. eQTL data for 19,960 genes were obtained from the eQTLGen study. Next, eQTLs displayin...

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Hovedforfatter: Majid Nikpay
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-07-01
Serier:Current Issues in Molecular Biology
Fag:
trans-eQTLs
tissue specificity
gene regulatory network
mendelian randomization
scale-free network
Online adgang:https://www.mdpi.com/1467-3045/47/8/594
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