Production and Quality Control of [¹⁷⁷Lu]Lu-PSMA-I&T: Development of an Investigational Medicinal Product Dossier for Clinical Trials

Since prostate cancer is the most commonly diagnosed malignancy in men, the theranostic approach has become very attractive since the discovery of urea-based PSMA inhibitors. Different molecules have been synthesized starting from the Glu-urea-Lys scaffold as the pharmacophore and then optimizing th...

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Principais autores:	Valentina Di Iorio, Stefano Boschi, Cristina Cuni, Manuela Monti, Stefano Severi, Giovanni Paganelli, Carla Masini
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-06-01
Colecção:	Molecules
Assuntos:	prostate cancer [<sup>177</sup>Lu]Lu-PSMA-I&T IMPD quality assurance
Acesso em linha:	https://www.mdpi.com/1420-3049/27/13/4143
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