GSRF-DTI: a framework for drug-target interaction prediction based on a drug-target pair network and representation learning on a large graph

Abstract Background Identification of potential drug-target interactions (DTIs) with high accuracy is a key step in drug discovery and repositioning, especially concerning specific drug targets. Traditional experimental methods for identifying the DTIs are arduous, time-intensive, and financially bu...

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Bibliografiske detaljer

Principais autores:	Yongdi Zhu, Chunhui Ning, Naiqian Zhang, Mingyi Wang, Yusen Zhang
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2024-07-01
Serier:	BMC Biology
Fag:	Drug-target interaction Graph representation learning Graph neural network Machine learning
Online adgang:	https://doi.org/10.1186/s12915-024-01949-3
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