Development of super-specific epigenome editing by targeted allele-specific DNA methylation
Abstract Background Epigenome editing refers to the targeted reprogramming of genomic loci using an EpiEditor which may consist of an sgRNA/dCas9 complex that recruits DNMT3A/3L to the target locus. Methylation of the locus can lead to a modulation of gene expression. Allele-specific DNA methylation...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
BMC
2023-10-01
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| Цуврал: | Epigenetics & Chromatin |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://doi.org/10.1186/s13072-023-00515-5 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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