Differential effects of class I antiarrhythmic drugs on the guinea pig pulmonary vein myocardium: Inhibition of automatic activity correlates with blockade of a diastolic sodium current component

The effects of class I antiarrhythmic drugs on the automaticity of isolated guinea pig pulmonary vein myocardia were investigated using microelectrode and voltage clamp methods. All of the drugs examined reduced the maximum rate of rise of automatic action potentials. The firing frequency and rate o...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Masahiko Irie, Haruhito Hiiro, Shu Kato, Mizuki Kuramochi, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2020-08-01
Цуврал:	Journal of Pharmacological Sciences
Нөхцлүүд:	Pulmonary vein automaticity Class I antiarrhythmics Diastolic sodium current component
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1347861320300487
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!