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Mechanical gating of tendon fibrogenic transcription in systemic sclerosis

Abstract Fibrosis arises from aberrant tissue repair in systemic sclerosis and is characterized by progressive stiffening across multiple tissues, including tendons. How altered tissue mechanics sustain fibrotic remodeling remains poorly understood, in part because of limited experimental models tha...

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Bibliografski detalji
Glavni autori: Amro A. Hussien, Robert Knell, Stefania L. Wunderli, Matthew R. Aronoff, Barbara Niederoest, Florian Renoux, Amela Hukara, Jasper Foolen, Helma Wennemers, Oliver Distler, Jess G. Snedeker
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2026-03-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-026-70395-2
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