Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin

Changes in DNA methylation patterning have been reported to be a key hallmark of aged human skin. The altered DNA methylation patterns are correlated with deregulated gene expression and impaired tissue functionality, leading to the well-known skin aging phenotype. Searching for small molecules, whi...

Descripció completa

Dades bibliogràfiques

Autors principals:	Cassandra Falckenhayn, Agata Bienkowska, Jörn Söhle, Katrin Wegner, Guenter Raddatz, Boris Kristof, Dirk Kuck, Ralf Siegner, Ronny Kaufmann, Julia Korn, Sascha Baumann, Daniela Lange, Andreas Schepky, Henry Völzke, Lars Kaderali, Marc Winnefeld, Frank Lyko, Elke Grönniger
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-03-01
Col·lecció:	Frontiers in Aging
Matèries:	dihydromyricetin DNMT1 inhibition DNA methylation DNAm age clock skin rejuvenation
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fragi.2023.1258184/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!