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Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells

We have studied the effect of human recombinant tumour necrosis factor-α (TNF-α) on gene expression and production of endothelin-1 in cultured bovine aortic endothelial cells. TNF-α (10 and 100 ng ml−1) increased in a time dependent manner the preproendothelin-1 mRNA levels in respect to unstimulate...

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Autores principales: Silvia Orisio, Marina Morigi, Carla Zoja, Norberto Perico, Giuseppe Remuzzi
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 1992-01-01
Colección:Mediators of Inflammation
Acceso en línea:http://dx.doi.org/10.1155/S0962935192000401
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