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Navigating collateral sensitivity: insights into the mechanisms and applications of antibiotic resistance trade-offs

The swift rise of antibiotic resistance, coupled with limited new antibiotic discovery, presents a significant hurdle to global public health, demanding innovative therapeutic solutions. Recently, collateral sensitivity (CS), the phenomenon in which resistance to one antibiotic increases vulnerabili...

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Principais autores: Hafij Al Mahmud, Catherine A. Wakeman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-10-01
coleção:Frontiers in Microbiology
Assuntos:
collateral sensitivity
antibiotic resistance trade-off
antibiotic therapy
CS mechanism
clinical implication
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1478789/full
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