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Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice.

In the last decades, few mechanistically novel therapeutic agents have been developed to treat mental and neurodegenerative disorders. Numerous studies suggest that targeting BDNF and its TrkB receptor could be a promising therapeutic strategy for the treatment of brain disorders. However, the devel...

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Xehetasun bibliografikoak
Egile Nagusiak: Maxime Cazorla, Anne Jouvenceau, Christiane Rose, Jean-Philippe Guilloux, Catherine Pilon, Alex Dranovsky, Joël Prémont
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2010-03-01
Saila:PLoS ONE
Sarrera elektronikoa:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009777&type=printable
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