An esterase-responsive ibuprofen nano-micelle pre-modified embryo derived nucleus pulposus progenitor cells promote the regeneration of intervertebral disc degeneration

Stem cell-based transplantation is a promising therapeutic approach for intervertebral disc degeneration (IDD). Current limitations of stem cells include with their insufficient cell source, poor proliferation capacity, low nucleus pulposus (NP)-specific differentiation potential, and inability to a...

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Detalhes bibliográficos

Principais autores:	Kai-shun Xia, Dong-dong Li, Cheng-gui Wang, Li-wei Ying, Jing-kai Wang, Biao Yang, Jia-wei Shu, Xian-peng Huang, Yu-ang Zhang, Chao Yu, Xiao-peng Zhou, Fang-cai Li, Nigel K.H. Slater, Jian-bin Tang, Qi-xin Chen, Cheng-zhen Liang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2023-03-01
Colecção:	Bioactive Materials
Assuntos:	Intervertebral disc degeneration Nucleus pulposus progenitor cells Esterase-responsive nano micell Biomaterial pre-modification Synergistic transplantation therapy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452199X22003218
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