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Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma

<p>Abstract</p> <p>Background</p> <p>Alterations of mTOR gene expression have been implicated in the pathogenesis of endometrioid endometrial cancer however only few studies explored the cause of increased mTOR activation in this malignancy. miRNAs are small, noncoding RNAs, which were proven to reg...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Torres Anna, Torres Kamil, Pesci Anna, Ceccaroni Marcello, Paszkowski Tomasz, Cassandrini Paola, Zamboni Giuseppe, Maciejewski Ryszard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2012-08-01
Schriftenreihe:BMC Cancer
Schlagworte:
mTOR
microRNA
miRNA
Endometrial cancer
Plasma
Online-Zugang:http://www.biomedcentral.com/1471-2407/12/369
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