Agent-Based Modeling of Autosomal Recessive Deafness 1A (DFNB1A) Prevalence with Regard to Intensity of Selection Pressure in Isolated Human Population

An increase in the prevalence of autosomal recessive deafness 1A (DFNB1A) in populations of European descent was shown to be promoted by assortative marriages among deaf people. Assortative marriages became possible with the widespread introduction of sign language, resulting in increased genetic fi...

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Hlavní autoři:	Georgii P. Romanov, Anna A. Smirnova, Vladimir I. Zamyatin, Aleksey M. Mukhin, Fedor V. Kazantsev, Vera G. Pshennikova, Fedor M. Teryutin, Aisen V. Solovyev, Sardana A. Fedorova, Olga L. Posukh, Sergey A. Lashin, Nikolay A. Barashkov
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-02-01
Edice:	Biology
Témata:	agent-based computer modeling hereditary deafness <i>GJB2</i> genetic fitness assortative mating sign language
On-line přístup:	https://www.mdpi.com/2079-7737/11/2/257
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