RAP-peptide functionalized biomimetic nanoformulation with pathological ROS/pH-responsive drug release for target immunotherapy in glioma

Abstract Glioblastoma (GBM) is one of the most aggressive malignancies of the central nervous system. Gemcitabine (GEM), a pyrimidine analogue with broad-spectrum anticancer activity, can activate the cGAS-STING pathway and alleviate the immunosuppressive microenvironment of GBM. However, its clinic...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yunfan Li, Kaiwen Bao, Renzheng Huan, Tian Wang, Ya Wang, Shuai Wu, Xin Chen, Jiashang Huang, Li Zhu, Jianshu Li, Haifeng Yang, Wei Wu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2026-02-01
Sarja:	Journal of Nanobiotechnology
Aiheet:	Glioblastoma Immunotherapy Biomimetic nanoformulation Tumor microenvironment remodeling Blood-brain barrier
Linkit:	https://doi.org/10.1186/s12951-026-04055-4
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!