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Parahydrogen‐Polarized [1‐13C]Pyruvate for Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging

Abstract Hyperpolarization techniques increase nuclear spin polarization by more than four orders of magnitude, enabling metabolic MRI. Even though hyperpolarization has shown clear value in clinical studies, the complexity, cost and slowness of current equipment limits its widespread use. Here, a p...

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Glavni autori: Luca Nagel, Martin Gierse, Wolfgang Gottwald, Zumrud Ahmadova, Martin Grashei, Pascal Wolff, Felix Josten, Senay Karaali, Christoph A. Müller, Sebastian Lucas, Jochen Scheuer, Christoph Müller, John Blanchard, Geoffrey J. Topping, Andre Wendlinger, Nadine Setzer, Sandra Sühnel, Jonas Handwerker, Christophoros Vassiliou, Frits H.A. vanHeijster, Stephan Knecht, Michael Keim, Franz Schilling, Ilai Schwartz
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2023-10-01
Serija:Advanced Science
Teme:
hyperpolarization
metabolic imaging
magnetic resonance imaging (MRI)
parahydrogen
pyruvate
Online pristup:https://doi.org/10.1002/advs.202303441
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