Elevated glutamine but not glutamate is associated with clozapine eligibility in an early psychosis sample

IntroductionApproximately one-third of individuals with schizophrenia will meet the criteria for treatment-resistant schizophrenia (TRS), the majority of whom demonstrate poor pharmacological response early in their course of illness. Clozapine response is higher when used early in the illness traje...

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Κύριοι συγγραφείς:	Maxwell Seward, Esther Puiras, Temi Toba-Oluboka, Candice E. Crocker, Philip G. Tibbo, Kara Dempster
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2026-02-01
Σειρά:	Frontiers in Psychiatry
Θέματα:	anterior cingulate cortex clozapine eligibility early phase psychosis glutamate glutamine magnetic resonance spectroscopy
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1762696/full
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