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Uremic Apelin and Leucocytic Angiotensin-Converting Enzyme 2 in CKD Patients

Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its vaso...

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Bibliografiska uppgifter
Huvudupphov: Bogusz Trojanowicz, Christof Ulrich, Matthias Girndt
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2020-11-01
Serie:Toxins
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Länkar:https://www.mdpi.com/2072-6651/12/12/742
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