Functionalized 10-Membered Aza- and Oxaenediynes through the Nicholas Reaction

The scope and limitations of the Nicholas-type cyclization for the synthesis of 10-membered benzothiophene-fused heterocyclic enediynes with different functionalities were investigated. Although the Nicholas cyclization through oxygen could be carried out in the presence of an ester group, the final...

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Detalhes bibliográficos

Principais autores:	Natalia A. Danilkina, Ekaterina A. Khmelevskaya, Anna G. Lyapunova, Alexander S. D’yachenko, Alexander S. Bunev, Rovshan E. Gasanov, Maxim A. Gureev, Irina A. Balova
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-09-01
coleção:	Molecules
Assuntos:	alkynes enediynes heterocycles benzo[<i>b</i>]thiophene Bergman cyclization Nicholas reaction
Acesso em linha:	https://www.mdpi.com/1420-3049/27/18/6071
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