Subtractive genomic approach to uncover novel drug targets in Salmonella typhimurium and computational screening of food-based polyphenols as inhibitors

IntroductionThe rise of multidrug-resistant Salmonella typhimurium is a severe public health threat that renders conventional antibiotics ineffective. This study employed a computational strategy to identify a novel drug target in S. typhimurium and screen food-based polyphenols as potential inhibit...

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Principais autores:	Mohammed Naveez Valathoor, Subhashree Venugopal, Anand Prem Rajan
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-12-01
Serija:	Frontiers in Bioinformatics
Teme:	subtractive genome Salmonella typhimurium food-based polyphenols molecular docking molecular dynamic simulation
Online dostop:	https://www.frontiersin.org/articles/10.3389/fbinf.2025.1695217/full
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