Puerarin Inhibits Proliferation, Migration and Invasion of Colon Cancer Cells and Induces Apoptosis via Suppression of the PI3K/AKT Signaling Pathway

<b>Background</b>: Colon cancer is one of the most prevalent gastrointestinal malignancies worldwide, with high mortality and limited therapeutic options. Puerarin, a flavonoid compound derived from <i>Pueraria lobata</i>, has shown anticancer potential, but its molecular mec...

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Main Authors: Lin Chen, Xuhong Li, Shijie Zhao, Mengyu Hao, Heng Wang, Zhi Zhou, Xinyu Xiong, Die Yuan, Piao Luo, Luwen Wang, Di Pan, Xiangchun Shen, Yue Zhang, Yan Chen
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-09-01
Series:Pharmaceuticals
Assuntos:
puerarin
colon cancer
PI3K/AKT
epithelial–mesenchymal transition
apoptosis
Acceso en liña:https://www.mdpi.com/1424-8247/18/9/1378
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