How (5′S) and (5′R) 5′,8-Cyclo-2′-Deoxypurines Affect Base Excision Repair of Clustered DNA Damage in Nuclear Extracts of xrs5 Cells? A Biochemical Study

The clustered DNA lesions (CDLs) are a characteristic feature of ionizing radiation’s impact on the human genetic material. CDLs impair the efficiency of cellular repair machinery, especially base excision repair (BER). When CDLs contain a lesion repaired by BER (e.g., apurinic/apyrimidinic (AP) sit...

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Detalhes bibliográficos

Principais autores:	Karolina Boguszewska, Michał Szewczuk, Julia Kaźmierczak-Barańska, Bolesław T. Karwowski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-03-01
coleção:	Cells
Assuntos:	BER 5′,8-cyclo-2′-deoxyadenosine (cdA) 5′,8-cyclo-2′-deoxyguanosine (cdG) DNA repair clustered DNA damage
Acesso em linha:	https://www.mdpi.com/2073-4409/10/4/725
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