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Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening

False-positives plague high-throughput screening in general and are costly as they consume resource and time to resolve. Methods that can rapidly identify such compounds at the initial screen are therefore of great value. Advances in mass spectrometry have led to the ability to screen inhibitors in...

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Autors principals: De Lin, Lesley-Anne Pearson, Shamshad Ahmad, Sandra O’Neill, John Post, Colin Robinson, Duncan E. Scott, Ian H. Gilbert
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2025-09-01
Col·lecció:SLAS Discovery
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2472555225000450
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