Post-mortem brain histological examination in the substantia nigra and subthalamic nucleus in Parkinson’s disease following deep brain stimulation

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, pathologically hallmarked by the loss of dopamine neurons in the substantia nigra (SN) and alpha-synuclein aggregation. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a common target to treat the motor symptoms i...

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Главные авторы:	Srestha Mazumder, Anita Y. Bahar, Claire E. Shepherd, Asheeta A. Prasad
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2022-09-01
Серии:	Frontiers in Neuroscience
Предметы:	Parkinson’s disease deep brain stimulation subthalamic nucleus substantia nigra alpha-synuclein
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fnins.2022.948523/full
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