Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopyResearch in context

Summary: Background: Inflammatory demyelinating diseases of the central nervous system, such as multiple sclerosis, are significant sources of morbidity in young adults despite therapeutic advances. Current murine models of remyelination have limited applicability due to the low white matter conten...

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Ngā kaituhi matua:	Mihai Ancău, Goutam Kumar Tanti, Vicki Marie Butenschoen, Jens Gempt, Igor Yakushev, Stephan Nekolla, Mark Mühlau, Christian Scheunemann, Sebastian Heininger, Benjamin Löwe, Erik Löwe, Silke Baer, Johannes Fischer, Judith Reiser, Sai S. Ayachit, Friederike Liesche-Starnecker, Jürgen Schlegel, Kaspar Matiasek, Martina Schifferer, Jan S. Kirschke, Thomas Misgeld, Tim Lueth, Bernhard Hemmer
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2024-02-01
Rangatū:	EBioMedicine
Ngā marau:	In vivo minipig model Lysophosphatidylcholine Inflammatory-demyelinating brain disease PET/MRI Scanning electron microscopy Electromagnetic-guided navigation system
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2352396424000173
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