Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia

Persistence of IDH1 or IDH2 mutations in remission bone marrow specimens of patients with acute myeloid leukemia has been observed, but the clinical impact of these mutations is not well known. In this study, we evaluated 80 acute myeloid leukemia patients with known IDH1 R132 or IDH2 R140/R172 muta...

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Hlavní autoři:	Chi Young Ok, Sanam Loghavi, Dawen Sui, Peng Wei, Rashmi Kanagal-Shamanna, C. Cameron Yin, Zhuang Zuo, Mark J. Routbort, Guilin Tang, Zhenya Tang, Jeffrey L. Jorgensen, Rajyalakshmi Luthra, Farhad Ravandi, Hagop M. Kantarjian, Courtney D. DiNardo, L. Jeffrey Medeiros, Sa A. Wang, Keyur P. Patel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Ferrata Storti Foundation 2019-02-01
Edice:	Haematologica
On-line přístup:	https://haematologica.org/article/view/8773
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