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A tubulin binding molecule drives differentiation of acute myeloid leukemia cells

Summary: Despite much progress in developing better drugs, many patients with acute myeloid leukemia (AML) still die within a year of diagnosis. This is partly because it is difficult to identify therapeutic targets that are effective across multiple AML subtypes. One common factor across AML subtyp...

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Principais autores: Thomas R. Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S. Madden, Daniel Conole, Thomas J. Cogswell, Isabel V.L. Wilkinson, Laura M. Kettyle, Douzi Zhang, Alison O’Mahony, Deanne Gracias, Lorna McCall, Robert Westwood, Georg C. Terstappen, Stephen G. Davies, Edward W. Tate, Graham M. Wynne, Paresh Vyas, Angela J. Russell, Thomas A. Milne
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-08-01
coleção:iScience
Assuntos:
Chemistry
Biological sciences
Molecular biology
Molecular medicine
Cancer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004222010598
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