Modulating Neuro-Immune-Induced Macrophage Polarization With Topiramate Attenuates Experimental Abdominal Aortic Aneurysm

The development of abdominal aortic aneurysm (AAA) is attributed to psychological and physical factors. Topiramate, which is an agonist of the GABAA receptor, makes contributions to neuronal disease and is partially involved in immune regulation, may be effective upon abdominal aortic aneurysm progr...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Xing Chen, Yang Li, Jie Xiao, Hua Zhang, Chuanlei Yang, Zhanjie Wei, Weiqiang Chen, Xinling Du, Jinping Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2020-08-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	abdominal aortic aneurysm topiramate γ-aminobutyric acid neuro-immune macrophage polarization
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fphar.2020.565461/full
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