An open-label study evaluating the safety, behavioral, and electrophysiological outcomes of low-dose ketamine in children with ADNP syndrome

Summary: Activity-dependent neuroprotective protein (ADNP) syndrome is a rare genetic condition associated with intellectual disability and autism spectrum disorder. Preclinical evidence suggests that low-dose ketamine may induce expression of ADNP and that neuroprotective effects of ketamine may be...

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Hlavní autoři:	Alexander Kolevzon, Tess Levy, Sarah Barkley, Sandra Bedrosian-Sermone, Matthew Davis, Jennifer Foss-Feig, Danielle Halpern, Katherine Keller, Ana Kostic, Christina Layton, Rebecca Lee, Bonnie Lerman, Matthew Might, Sven Sandin, Paige M. Siper, Laura G. Sloofman, Hannah Walker, Jessica Zweifach, Joseph D. Buxbaum
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-10-01
Edice:	HGG Advances
Témata:	Helsmoortel-Van der Aa syndrome ADNP ketamine autism spectrum disorder ASD
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2666247722000549
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