OGDH primes macrophage for M1-like polarization and ferroptosis in sepsis associated acute lung injury
Abstract Background Sepsis-associated acute lung injury (S-ALI) is a clinical syndrome characterized by dysregulated inflammation and overwhelming oxidative stress, and is associated with a poor prognosis. Alpha-ketoglutarate dehydrogenase (OGDH) is a key enzyme in the tricarboxylic acid cycle that...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BMC
2026-05-01
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| Reeks: | Respiratory Research |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1186/s12931-026-03720-4 |
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