Pro-inflammatory wnt5a and anti-inflammatory sFRP5 are differentially regulated by nutritional factors in obese human subjects.

<h4>Background</h4>Obesity is associated with macrophage infiltration of adipose tissue. These inflammatory cells affect adipocytes not only by classical cytokines but also by the secreted glycopeptide wnt5a. Healthy adipocytes are able to release the wnt5a inhibitor sFRP5. This protective effect, h...

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Principais autores:	Dominik M Schulte, Nike Müller, Katrin Neumann, Frank Oberhäuser, Michael Faust, Heike Güdelhöfer, Burkhard Brandt, Wilhelm Krone, Matthias Laudes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032437&type=printable
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