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Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins.

Vaccinia virus interferes with early events of the activation pathway of the transcriptional factor NF-kB by binding to numerous host TIR-domain containing adaptor proteins. We have previously determined the X-ray structure of the A46 C-terminal domain; however, the structure and function of the A46...

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Príomhchruthaitheoirí: Sofiya Fedosyuk, Gustavo Arruda Bezerra, Katharina Radakovics, Terry K Smith, Massimo Sammito, Nina Bobik, Adam Round, Lynn F Ten Eyck, Kristina Djinović-Carugo, Isabel Usón, Tim Skern
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2016-12-01
Sraith:PLoS Pathogens
Rochtain ar líne:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006079&type=printable
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