Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague.
Type I interferons (IFN-I) broadly control innate immunity and are typically transcriptionally induced by Interferon Regulatory Factors (IRFs) following stimulation of pattern recognition receptors within the cytosol of host cells. For bacterial infection, IFN-I signaling can result in widely varian...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2012-01-01
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| coleção: | PLoS Pathogens |
| Acesso em linha: | http://europepmc.org/articles/PMC3406097?pdf=render |
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