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The gut resistome as a potential determinant of immunotherapy response: antibiotics, immunometabolism, and precision oncology

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet their efficacy can be compromised by systemic antibiotic exposure and the resulting disruption of the gut microbiome. Across several tumor types, antibiotic use near the initiation of ICI therapy has frequently been associated...

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Autores principales: Min-Kyung Joo, Jihoon Tak, Suhyeon Ha, Kyung-sik Yoon, Jung-Man Namgoong, Hye Ok Kim
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2026-07-01
Colección:Frontiers in Microbiology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fmicb.2026.1835588/full
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