Swine RNF5 positively regulates the antiviral activity of IFITM1 by mediating the degradation of ABHD16A

ABSTRACT Interferon-inducible transmembrane (IFITM) proteins are broad-spectrum antiviral factors that confer cellular resistance to virus invasion. α/β-Hydrolase domain-containing 16A (ABHD16A) has recently been identified as a novel depalmitoylase that can inhibit the antiviral activity of IFITM p...

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Bibliographic Details
Main Authors: Xuemeng Shi, Lingyi Shen, Shuaiwu Chen, Mingyang Liu, Jingyi Wang, Xin Wen, Wei Liu, Lin Mao, Yunyun Ding, Li Yu, Jun Xu
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2025-01-01
Series:Journal of Virology
Subjects:
RNF5
ABHD16A
IFITM
post-translational modification
virus infection
Online Access:https://journals.asm.org/doi/10.1128/jvi.01277-24
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