Isolevuglandin-modified phosphatidylethanolamine is metabolized by NAPE-hydrolyzing phospholipase D

Lipid aldehydes including isolevuglandins (IsoLGs) and 4-hydroxynonenal modify phosphatidylethanolamine (PE) to form proinflammatory and cytotoxic adducts. Therefore, cells may have evolved mechanisms to degrade and prevent accumulation of these potentially harmful compounds. To test if cells could...

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Xehetasun bibliografikoak

Egile Nagusiak:	Lilu Guo, Stephen D. Gragg, Zhongyi Chen, Yongqin Zhang, Venkataraman Amarnath, Sean S. Davies
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2013-11-01
Saila:	Journal of Lipid Research
Gaiak:	isoketal N-acyl phosphatidylethanolamine cytotoxicity inflammation oxidative stress N-acyl ethanolamine
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S0022227520350665
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