Development and application of the physiologically-based toxicokinetic (PBTK) model for ochratoxin A (OTA) in rats and humans

Ochratoxin A (OTA) is a common fungal toxin frequently detected in food and human plasma samples. Currently, the physiologically based toxicokinetic (PBTK) model plays an active role in dose translation and can improve and enhance the risk assessment of toxins. In this study, the PBTK model of OTA i...

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Hauptverfasser:	Bu-Da Su, Xiao-Meng Li, Zhi-Wei Huang, Yue Wang, Jia Shao, Yan-Yan Xu, Le-Xin Shu, Yu-Bo Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-05-01
Schriftenreihe:	Ecotoxicology and Environmental Safety
Schlagworte:	Ochratoxin A human model inter-specific extrapolation dose translation
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0147651324003531
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