Modulating Protein–Protein Interactions by Cyclic and Macrocyclic Peptides. Prominent Strategies and Examples

Cyclic and macrocyclic peptides constitute advanced molecules for modulating protein–protein interactions (PPIs). Although still peptide derivatives, they are metabolically more stable than linear counterparts, and should have a lower degree of flexibility, with more defined secondary structure conf...

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Hlavní autoři:	Rosario González-Muñiz, María Ángeles Bonache, María Jesús Pérez de Vega
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-01-01
Edice:	Molecules
Témata:	cyclic peptides macrocyclic peptides protein–protein interactions computational design biochemical methodologies synthetic strategies
On-line přístup:	https://www.mdpi.com/1420-3049/26/2/445
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