Multiple Regulatory Layers of SREBP1/2 by SIRT6

The NAD+-dependent protein deacetylase SIRT6 regulates genome stability, cancer, and lifespan. Mice overexpressing SIRT6 (MOSES) have lower low-density lipoprotein cholesterol levels and are protected against the physiological damage of obesity. Here, we examined the role of SIRT6 in cholesterol reg...

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Bibliografski detalji

Glavni autori:	Sivan Elhanati, Yariv Kanfi, Alexander Varvak, Asael Roichman, Ilana Carmel-Gross, Shaul Barth, Gilad Gibor, Haim Y. Cohen
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2013-09-01
Serija:	Cell Reports
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2211124713004300
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