Cervicovaginal microbiome alters transcriptomic and chromatin accessibility signatures across cervicovaginal epithelial barriers

Abstract Background The cervicovaginal microbiome plays a critical role in women’s health with microbial communities dominated by Lactobacillus species considered optimal. In contrast, the depletion of lactobacilli and the presence of a diverse array of strict and facultative anaerobes, such as Gard...

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Principais autores:	Lauren Anton, Ana G. Cristancho, Briana Ferguson, Jacques Ravel, Michal A. Elovitz
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-11-01
Serija:	Microbiome
Teme:	Cervix Epithelial cells Lactobacillus crispatus Gardnerella vaginalis RNA-seq Anti-microbial peptides
Online dostop:	https://doi.org/10.1186/s40168-025-02223-6
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