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PSMC4 promotes low-grade glioma progression and predicts poor prognosis

Abstract Background Low-grade gliomas (LGG) are aggressive brain tumors with high rates of recurrence and poor prognosis. PSMC4, a proteasome subunit, plays a role in various cancers, but its function in LGG remains poorly understood. This study explores PSMC4's impact on LGG progression. Methods PS...

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Principais autores: Wang Ming, Si Yunhui, Cui Dongjuan, Zhao Yanhong, Bie Huijie, Zhao Hui, Qian Liquan, Du Zhongliang, Wang Liping
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-02-01
coleção:European Journal of Medical Research
Assuntos:
PSMC4
Low-grade glioma (LGG)
Prognosis
Tumor progression
Immune microenvironment
Acesso em linha:https://doi.org/10.1186/s40001-026-03914-y
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