Current Understanding of the Pathogenesis of ANCA-Associated Vasculitis and Novel Treatment Options Targeting Complement Activation

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (ANCA-vasculitis) is an autoimmune disease characterized by inflammation and necrosis of small or medium vessels. In the past, the role of the complement in the pathogenesis of ANCA-vasculitis has been underestimated, due to the pauci...

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Auteurs principaux:	Konstantinos Drouzas, Petros Kalogeropoulos, George Liapis, Sophia Lionaki
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2025-05-01
Collection:	Life
Sujets:	ANCA glomerulonephritis (ANCA-GN) granulomatosis with polyangiitis (GPA) microscopic polyangiitis (MPA) complement activation B-depletion avacopan
Accès en ligne:	https://www.mdpi.com/2075-1729/15/5/756
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